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  7. GPT Image 2 vs Nano Banana Pro: 10 Disciplines Tested in 2026
Tools & Comparison·2026-04-25·Updated 2026-04-25·23 min read

GPT Image 2 vs Nano Banana Pro: 10 Disciplines Tested in 2026

We tested GPT Image 2 and Nano Banana Pro across 10 scientific disciplines with 24 figures. See where each AI wins, fails, and which to choose.

SciFig Team

SciFig Team

Scientific Illustration Experts

On this page

  • GPT Image 2 and Nano Banana Pro at a Glance
  • GPT Image 2: OpenAI's Flagship for Detail-Heavy Figures
  • Nano Banana Pro: Google's Top Tier for Clean BioRender-Style Figures
  • Head-to-Head: 10 Disciplines, 24 Figures
  • Five Findings That Generalize
  • Verdict: Which Should You Choose?
  • Behind the Methodology
  • Frequently Asked Questions
We generated 24 scientific figures across 10 disciplines — from CRISPR-Cas9 cutting mechanisms to Transformer architectures, Hadley cell circulation to Möbius strip topology — using GPT Image 2 (OpenAI's flagship) and Nano Banana Pro (Google's Gemini 3 top tier). Each figure was graded on six dimensions: prompt fidelity, instruction adherence, scientific accuracy, publication readiness, readability, and aesthetic quality. The result, with all 12 prompts and 24 raw outputs published for replication, is the most thorough head-to-head test we know of for AI scientific illustration in 2026.

GPT Image 2 and Nano Banana Pro at a Glance

Both models are flagship image generators released by their respective parent companies in early 2026. SciFig integrates both via Kie.ai, so a single account lets you switch between them with one click in Text-to-Figure.
PropertyGPT Image 2Nano Banana Pro
Parent companyOpenAIGoogle (Gemini 3)
Mode variantsText-to-image, image-to-imageText-to-image, image-to-image
Aspect ratiosauto, 1:1, 9:16, 16:9, 4:3, 3:41:1, 2:3, 3:2, 3:4, 4:3, 4:5, 5:4, 9:16, 16:9, 21:9, auto
Resolutions1K, 2K, 4K1K, 2K, 4K
Native style hintsNone (driven by prompt)None (driven by prompt)
SciFig integration/models/gpt-image-2/models/nano-banana-pro
For this benchmark we locked both models to 16:9 aspect ratio at 2K resolution to make the visual comparison fair. The prompts were 1,100–1,800 characters each, written to mimic a real graduate student briefing an illustrator with full scientific detail — every receptor, every kinase, every transition state spelled out.

GPT Image 2: OpenAI's Flagship for Detail-Heavy Figures

GPT Image 2 inherits the long-prompt obsession that has defined OpenAI text models since GPT-4. In practice, that means the model treats every clause in your prompt as a checklist item — and it tries hard to land all of them in the final figure.

Strengths

  • Prompt fidelity averaged 99.2% across our 24 figures, meaning nearly every named element from a 1,500-character prompt appeared in the rendered output.
  • Chemistry notation is its quiet superpower: in the SN2 reaction test it rendered the double-dagger ‡ symbol on the transition state, labeled R and S configurations, drew the pentacoordinate carbon with three hydrogens in a trigonal plane, included a complete energy diagram inset with Ea labeled, and added a four-color legend mapping nucleophile / leaving group / carbon / hydrogen.
  • Math formulas, coordinate axes, and scale bars appear consistently — the black hole figure included Rs = 2GM/c², the Möbius strip showed the full parametric equation x(u,v) = (1+v/2·cos(u/2))·cos(u), and the Young's double-slit experiment carried d·sin(θ) = m·λ with the path-difference triangle drawn out.
Test: SN2 substitution mechanism
GPT Image 2: SN2 substitution mechanism with double-dagger transition state, pentacoordinate carbon, R/S stereochemistry, energy diagram inset, and four-color element legend
GPT Image 2: SN2 substitution mechanism with double-dagger transition state, pentacoordinate carbon, R/S stereochemistry, energy diagram inset, and four-color element legend

GPT Image 2 — every chemistry convention rendered: ‡ on the transition state, R/S annotation, pentacoordinate carbon with three trigonal-plane hydrogens, energy diagram with Ea, and a color-coded legend (nucleophile / leaving group / carbon / hydrogen).

Nano Banana Pro: SN2 substitution mechanism recognizable but missing double-dagger, R-S stereochemistry annotation, and color legend
Nano Banana Pro: SN2 substitution mechanism recognizable but missing double-dagger, R-S stereochemistry annotation, and color legend

Nano Banana Pro — recognizable as SN2 but the double-dagger, the R/S annotation, the "pentacoordinate" label, and the element-color legend are all missing. The output is clean and readable; it just isn't peer-review tight on chemistry conventions.

Test: Young's double-slit interference
GPT Image 2: Young's double-slit interference experiment with Huygens wavefronts, path difference triangle inset, observation screen at distance L, and full equation d sin theta equals m lambda
GPT Image 2: Young's double-slit interference experiment with Huygens wavefronts, path difference triangle inset, observation screen at distance L, and full equation d sin theta equals m lambda

GPT Image 2 — full physics-textbook treatment: monochromatic source, Huygens construction with circular wavefronts, path-difference geometry inset, fringe pattern with m = 0, ±1, ±2 labeled, the position formula y_m = mλL/d, and an explicit "constructive bright" / "destructive dark" classification.

Nano Banana Pro: Young's double-slit interference with Huygens wavefronts and equation but missing some labels
Nano Banana Pro: Young's double-slit interference with Huygens wavefronts and equation but missing some labels

Nano Banana Pro — geometry and Huygens construction are accurate (the path-difference triangle is highlighted in soft orange, which is visually elegant), but the screen-distance L, the constructive/destructive classification, and the position formula are dropped from the figure.

Limitations

  • Information density can spill over into clutter. Our CRISPR test panel scored 95% on prompt fidelity but only 3 out of 5 on readability — every requested label was present, just packed too tightly to scan at a glance.
  • No 3D layer-stacking effects. Architecture diagrams (like the Transformer) come out flat, with Add & Norm blocks rendered in 2D rather than the 3D-looking layer-repetition cues you sometimes see in Nano Banana Pro outputs.

Best Scientific Use Cases

  • Journal submissions where every label, equation, and legend must survive peer-review scrutiny
  • Chemistry papers requiring stereochemistry, transition states, or reaction mechanism diagrams
  • Abstract mathematics (topology, manifolds) where conceptual fidelity outweighs visual punch
  • Long-prompt workflows (>1,000 characters) — see our companion guide on Mastering Scientific AI Prompts for prompt strategies that work especially well with this model

Tip

For Cell-tier journals, GPT Image 2 paired with Vector Canvas for final cleanup is our recommended pipeline — heavy detail in, polished SVG out.

See AI Scientific Figure Generation in Action

Watch how researchers create publication-ready scientific figures from text descriptions.

Explore the Tool

Nano Banana Pro: Google's Top Tier for Clean BioRender-Style Figures

Nano Banana Pro is the strongest model in Google's Gemini 3 family for image synthesis. Where GPT Image 2 leans into specification, Nano Banana Pro leans into composition — its outputs feel like a senior illustrator distilled the prompt into a clean editorial figure.

Strengths

  • Readability averaged 4.67 out of 5 versus GPT Image 2's 4.25. The difference is consistent: every figure has more breathing room, larger labels, and less visual stacking.
  • Aesthetic refinement is best-in-class for the BioRender-style scientific illustration aesthetic. The microservices architecture diagram captured the Kafka topic, sidecar pattern, and observability stack with annotated business events (Order Created, Payment Processed) — turning a static architecture into a near-storytelling diagram.
  • Layer stacking visualization is genuinely better. In our Transformer test it rendered the Encoder Stack (Nx) and Decoder Stack (Nx) as visually-stacked layered blocks, with explicit K, V, Q arrows tracing the cross-attention path from encoder to decoder — a level of structural intuition the GPT Image 2 output didn't quite reach.
  • Process workflow figures benefit from a dual-panel design choice the model frequently makes: in the photolithography test it drew a top "detailed view" and bottom "simplified cross-section" for each of the six steps, which is how IEEE textbooks actually present semiconductor processes.
Test: Microservices system architecture
GPT Image 2: microservices architecture with Istio service mesh, API Gateway, polyglot databases, Kafka with partitions, and observability stack with explicit vendor labels
GPT Image 2: microservices architecture with Istio service mesh, API Gateway, polyglot databases, Kafka with partitions, and observability stack with explicit vendor labels

GPT Image 2 — vendor-rich technical reference: API Gateway labeled "Kong / Envoy", Auth labeled "Keycloak", Istio Service Mesh wrapping all five services with explicit Envoy sidecars, Kafka shown with four partitions, and the observability stack split into Loki / Prometheus / Jaeger with a side legend.

Nano Banana Pro: microservices architecture with business event labels like Order Created and Payment Processed showing async event flow
Nano Banana Pro: microservices architecture with business event labels like Order Created and Payment Processed showing async event flow

Nano Banana Pro — adds a creative narrative layer: instead of just labeling the message queue "Kafka Topics", it annotates the actual business events flowing through it (Order Created, Order Updated, Payment Processed, Update Inventory, Send Notification). The architecture turns from static diagram into a near-storytelling figure.

Test: Semiconductor photolithography process
GPT Image 2: photolithography process as 6 horizontal panels showing spin coat soft bake UV exposure post-bake development etching with photomask UV source and developer
GPT Image 2: photolithography process as 6 horizontal panels showing spin coat soft bake UV exposure post-bake development etching with photomask UV source and developer

GPT Image 2 — single-row 6-panel sequence with consistent layer stacking (Si / SiO₂ / photoresist) across all stages. Compact and clear, but only one cross-section view per step.

Nano Banana Pro: photolithography process as 6 dual-panel columns showing detailed view above and simplified cross-section below for each step
Nano Banana Pro: photolithography process as 6 dual-panel columns showing detailed view above and simplified cross-section below for each step

Nano Banana Pro — same 6 steps but each rendered as a dual panel: detailed view on top, simplified cross-section below. This is how IEEE textbooks actually present photolithography. Bonus details like water-vapor symbols during soft-bake and "exposed regions (more soluble)" labels make this output the highest-scoring engineering figure in our benchmark (19/20).

Limitations

  • Prompt fidelity averaged 86.1% — about 13 percentage points behind GPT Image 2. Specifically, it tends to drop optional labels, color-key legends, and explicit numeric annotations when the prompt is long.
  • Chemistry rigor is its weakest area. In the SN2 test it omitted the double-dagger transition-state marker, the R/S stereochemistry annotation, the four-color element legend, and the explicit "pentacoordinate transition state" label — all things GPT Image 2 included.
  • 3D abstract topology can fail. Our Möbius strip test is the most striking example: Nano Banana Pro rendered the main figure as a plain orientable cylinder (no half-twist) and only included the actual Möbius strip in a small inset — a conceptual error severe enough to mislead a student reader. GPT Image 2 got this right on the first try.
Test: Möbius strip topology (the failure case worth seeing)
GPT Image 2: Möbius strip rendered in 3D with visible half-twist, red ant tracing the surface to demonstrate one-sidedness, full parametric equation, and orientable cylinder inset for comparison
GPT Image 2: Möbius strip rendered in 3D with visible half-twist, red ant tracing the surface to demonstrate one-sidedness, full parametric equation, and orientable cylinder inset for comparison

GPT Image 2 — a believable 3D Möbius strip with the half-twist clearly visible. Red ant markers at "start" and "after 180°" demonstrate one-sidedness; the boundary is rendered as a single continuous curve. The cylinder is in the corner inset for comparison, with annotations "two distinct edges" and "two-sided surface". Score: 20/20.

Nano Banana Pro: incorrectly rendered as a plain cylinder with no half-twist, with the actual Möbius strip relegated to a small corner inset
Nano Banana Pro: incorrectly rendered as a plain cylinder with no half-twist, with the actual Möbius strip relegated to a small corner inset

Nano Banana Pro — the main figure is an ordinary orientable cylinder, not a Möbius strip. The actual Möbius strip is shrunken into a tiny corner inset. This is a conceptual error severe enough to mislead any student reading the figure. Score: 11/20 — our second-largest single-prompt gap.

Best Scientific Use Cases

  • Conference posters, slide decks, and teaching materials where readability beats dense annotation
  • Biology mechanism diagrams (signaling pathways, mechanism cartoons) where BioRender-style simplicity is the genre convention
  • ML/CS architecture figures where layer stacking and data-flow arrows matter
  • Process workflow figures where dual-panel "detail + simplified" presentation aids comprehension

Head-to-Head: 10 Disciplines, 24 Figures

Before the table, here is the only test that ended in a tie — both flagships hit Nature-cover quality on the same prompt:

Test: Plate tectonics cross-section (the tie)
GPT Image 2: plate tectonics cross-section showing divergent convergent and transform boundaries with mantle convection cells lithosphere asthenosphere distinction and depth scale National Geographic style
GPT Image 2: plate tectonics cross-section showing divergent convergent and transform boundaries with mantle convection cells lithosphere asthenosphere distinction and depth scale National Geographic style

GPT Image 2 — three boundary types side by side with strong volumetric depth, lithosphere/asthenosphere temperature gradient, mantle convection cells. National Geographic / USGS style. Score: 19/20.

Nano Banana Pro: plate tectonics cross-section with hydrothermal vent biological communities and slab dehydration zone labels and clean even spacing
Nano Banana Pro: plate tectonics cross-section with hydrothermal vent biological communities and slab dehydration zone labels and clean even spacing

Nano Banana Pro — same scientific accuracy on the three boundary types, with a bonus level of ecological detail (hydrothermal vent biology, sulfide chimneys) and explicit "Slab Dehydration Zone" annotation. Cleaner label spacing. Score: 19/20.

We ran 12 prompts across 10 disciplines, generated each at 16:9 / 2K with both models, and scored every output. Below is the full result. Subjective scores are on a 1–5 scale per dimension; total is the sum of four subjective dimensions (max 20).

PromptDisciplineGPT Image 2 fidelityNBP fidelityGPT Image 2 totalNBP totalWinner
EGFR / RAS / MAPK signalingBiomedical100%80%1918GPT Image 2
CRISPR-Cas9 cuttingBiomedical95%98%1518Nano Banana Pro
Transformer architectureCS100%95%1618Nano Banana Pro
Microservices architectureCS100%85%1918GPT Image 2
SN2 substitutionChemistry100%70%2015GPT Image 2 (decisive)
Young's double-slitPhysics100%75%1918GPT Image 2
Photolithography processEngineering95%100%1719Nano Banana Pro
Plate tectonics cross-sectionEarth Science100%95%1919Tie
Möbius strip topologyMathematics100%80%2011GPT Image 2 (NBP rendering error)
Black hole accretion diskAstronomy100%80%1918GPT Image 2
Forest food webEcology100%90%1918GPT Image 2
Hippocampus / LTPNeuroscience100%85%1918GPT Image 2
Tally: GPT Image 2 wins 8 (including 2 decisively); Nano Banana Pro wins 3; one tie.
The aggregate gap on prompt fidelity (99.2% vs 86.1%) is the most telling number — it tells you that the longer your prompt, the more consistently GPT Image 2 will land all the requested elements. But the subjective totals (89/100 vs 88/100) tell you something different: when both models do hit the requested elements, the resulting figures are roughly equally good, just stylistically different.
You can browse all 24 figures with their full prompts at /inspiration?model=gpt-image-2 and /inspiration?model=nano-banana-pro. Every figure on those pages was generated for this benchmark — you can copy the prompt and re-run either model yourself.

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Five Findings That Generalize

1. Long-prompt fidelity is GPT Image 2's signature edge

When we compared the average prompt length (1,400 characters) against the fidelity gap (13.1 percentage points), the pattern was consistent: the longer and more specific the prompt, the more elements Nano Banana Pro tended to drop. This is not a small effect — over 12 prompts, GPT Image 2 hit 99.2% of named elements while Nano Banana Pro hit 86.1%.

If you write minimal prompts ("a cell signaling pathway diagram"), the gap shrinks. If you write the kind of rich, fully-specified prompts that we recommend in the SciFig prompt framework, the gap is real and reproducible.
Test: Northern temperate forest food web (a long-prompt benchmark)
GPT Image 2: forest food web with four trophic levels solar energy input species illustrations decomposers separate column and energy transfer percentage legend showing 10 percent rule
GPT Image 2: forest food web with four trophic levels solar energy input species illustrations decomposers separate column and energy transfer percentage legend showing 10 percent rule

GPT Image 2 — every species named in the 1,600-character prompt landed: oak, maple, ferns, grass, wildflowers, mosses (producers); white-tailed deer, snowshoe rabbit, gray squirrel, field mouse, caterpillar, bee, leaf beetle (herbivores); red fox, great horned owl, garter snake, songbird (warbler), shrew (mesopredators); gray wolf, red-tailed hawk, black bear (apex). Decomposers in a separate right column with bracket fungi / earthworms / bacteria. Energy transfer legend (100% → 10% → 1% → 0.1%) is intact.

Nano Banana Pro: forest food web with four trophic levels and species illustrations and organic matter return arrow but missing energy transfer percentage legend
Nano Banana Pro: forest food web with four trophic levels and species illustrations and organic matter return arrow but missing energy transfer percentage legend

Nano Banana Pro — same four trophic levels, same kcal/m²/year scale, all species recognizable. But it dropped the bracket-fungi / bacteria distinction, dropped the energy-transfer percentage legend, and only labeled "earthworm" rather than the full decomposer column. Caught the broad strokes; missed the textbook-grade footnotes.

2. Chemistry notation is GPT Image 2's quiet moat

The SN2 mechanism test produced our largest single-prompt gap (20 vs 15). GPT Image 2 rendered every standard chemistry convention — double-dagger, partial bonds, R/S stereochemistry, pentacoordinate geometry, energy diagram, color-coded element legend. Nano Banana Pro produced a recognizable mechanism, but missed the double-dagger, omitted the stereochemistry annotation, and didn't draw the legend.

For chemistry papers heading to JACS, Angewandte Chemie, or Organic Letters, this is the kind of detail that gets caught in peer review. For chemistry, choose GPT Image 2.

3. Abstract 3D topology can break Nano Banana Pro

Our Möbius strip test produced the most surprising result of the benchmark. The prompt asked for a 3D-rendered Möbius strip showing the half-twist, with a small inset comparing it to a regular cylinder. GPT Image 2 produced exactly that. Nano Banana Pro produced the inverse: the main figure was a plain cylinder with no twist, while the actual Möbius strip appeared only in a tiny inset.
This is more than a stylistic preference — it's a conceptual error severe enough to mislead a student. For abstract mathematics, choose GPT Image 2. When in doubt, generate from both and visually verify.

4. BioRender-style simplicity is Nano Banana Pro's home turf

Three of the model's wins (CRISPR-Cas9, Transformer, photolithography) share a common pattern: the prompt rewards simplification. CRISPR is a 4-step mechanism — Nano Banana Pro's clean step-by-step visual won over GPT Image 2's denser version. Transformer is a structural diagram — Nano Banana Pro's stacked-layer rendering captured the architecture intuition better.

If you're building slides for a 10-minute conference talk, where each figure has 30 seconds of attention, Nano Banana Pro is often the better default.
Test: CRISPR-Cas9 cutting mechanism (BioRender win for Nano Banana Pro)
GPT Image 2: CRISPR-Cas9 cutting mechanism in 4 sequential steps with detailed Cas9 protein rendering HNH RuvC nuclease domains PAM NGG sequence and NHEJ HDR repair pathways
GPT Image 2: CRISPR-Cas9 cutting mechanism in 4 sequential steps with detailed Cas9 protein rendering HNH RuvC nuclease domains PAM NGG sequence and NHEJ HDR repair pathways

GPT Image 2 — every requested element is present: Cas9 with HNH and RuvC domains, sgRNA with 20-nt target-complementary sequence, PAM (5'-NGG-3') highlighted, R-loop formation, blunt double-strand break "3 nt upstream of PAM", and both NHEJ and HDR repair pathways. Score: 15/20 — the lower readability hurt it because every label is packed in dense 3D rendering.

Nano Banana Pro: CRISPR-Cas9 cutting mechanism as 4 clean BioRender style steps with simplified Cas9 cartoon and clear NHEJ HDR repair pathway visualization
Nano Banana Pro: CRISPR-Cas9 cutting mechanism as 4 clean BioRender style steps with simplified Cas9 cartoon and clear NHEJ HDR repair pathway visualization

Nano Banana Pro — same 4-step structure, same scientific accuracy, but the BioRender-style flat illustration leaves much more breathing room. Each step has a single focal element. The NHEJ "indels for gene knockout" branch (red strike-through) and HDR "donor template insertion for gene correction" branch (green checkmark) are visually decisive. Score: 18/20 — the genre convention winner.

5. The information density / readability tradeoff is the deepest finding

Average scores across 24 figures expose two consistent profiles:

  • GPT Image 2: higher prompt fidelity (99.2%), higher publication readiness (4.58), lower readability (4.25)
  • Nano Banana Pro: lower prompt fidelity (86.1%), lower publication readiness (3.92), higher readability (4.67), highest aesthetic score (4.83)

Both are valid figure design philosophies — and they map onto two different end uses. GPT Image 2 is built for the figure that lives next to dense prose in a journal article. Nano Banana Pro is built for the figure that has to communicate on its own at 4 meters away in a conference hall.

Test: Hippocampus memory circuit and LTP (the trade-off in one image)
GPT Image 2: hippocampus trisynaptic circuit with EC DG CA3 CA1 subiculum anatomy and zoomed LTP mechanism showing NMDA AMPA receptors Ca2+ influx and CaMKII spine enlargement
GPT Image 2: hippocampus trisynaptic circuit with EC DG CA3 CA1 subiculum anatomy and zoomed LTP mechanism showing NMDA AMPA receptors Ca2+ influx and CaMKII spine enlargement

GPT Image 2 — title "Hippocampal Trisynaptic Circuit", anatomy on the left with EC Layer II / V-VI input/output specificity, four-step circuit numbered (Perforant Path → Mossy Fibers → Schaffer Collaterals → Output Path), zoomed LTP mechanism on the right with explicit "Resting Membrane Potential ~ -70 mV", four bullet-point molecular explanations, color legend in corner. Information density at its peak.

Nano Banana Pro: hippocampus memory circuit clean BioRender style with anatomy regions clearly demarcated and zoomed LTP mechanism showing baseline and LTP induction states with synapse strengthened spine enlargement result
Nano Banana Pro: hippocampus memory circuit clean BioRender style with anatomy regions clearly demarcated and zoomed LTP mechanism showing baseline and LTP induction states with synapse strengthened spine enlargement result

Nano Banana Pro — same anatomy, same circuit, same LTP mechanism. But each region is large, labels are spaced, and the eye has time to follow the data flow. Pyramidal neuron cell bodies and apical dendrites get explicit visual representation. The trade-off is the EC layer specificity (Layer II vs V-VI) and the -70 mV resting potential — both dropped. Result: same content, different reader experience.

Verdict: Which Should You Choose?

Default recommendation: GPT Image 2. Across the 12 prompts spanning 10 disciplines, GPT Image 2 won 8, tied 1, and lost only 3. Aggregate prompt fidelity 99.2% vs 86.1%, with two decisive routs — chemistry notation (20 vs 15) and abstract topology (20 vs 11) — in the exact domains where the wrong choice causes the most expensive rework on a real paper. The losses were on stylistic readability (CRISPR / Transformer / photolithography), not on scientific accuracy. For most researchers, GPT Image 2 is the safe default; pick Nano Banana Pro only when editorial polish outweighs notation rigor — typically slides, posters, and social media.

Use the decision tree below for edge cases. Different scientific work has different optimal model — match your figure type to one of the four common output destinations (peer-reviewed journal, conference, web, or "not sure"), then drill into the sub-rule for your specific discipline or figure genre.

  • Journal submission (Cell, Nature, Science, PNAS)
    • Chemistry / stereochemistry / reaction mechanism → GPT Image 2 (decisive)
    • Abstract mathematics / topology / manifolds → GPT Image 2 (NBP can fail conceptually)
    • Long, dense, label-heavy prompt → GPT Image 2
    • Biology mechanism in BioRender-style genre convention → Nano Banana Pro is acceptable, sometimes preferred
  • Slide deck / conference poster / teaching material
    • Default → Nano Banana Pro (readability + aesthetic edge)
    • ML / CS architecture → Nano Banana Pro (layer-stacking visual is stronger)
    • Process workflow with multiple steps → Nano Banana Pro (dual-panel design)
  • Blog or social media figure
    • Default → Nano Banana Pro (cleaner, scrolls better)
  • Cover-quality figure (high-end journal cover, National Geographic style)
    • Either model works; check our examples gallery to see comparable outputs and pick by aesthetic fit
  • You're not sure
    • SciFig supports both — just generate from each, side by side, and pick the winner. That's how a real human illustrator works anyway.
For broader context on how these two stack up against the rest of the AI scientific illustration landscape, see The 10 Best Scientific Illustration Tools in 2026, our P3 pillar guide.

Behind the Methodology

We tested 12 scientific prompts spanning 10 disciplines, locked at 16:9 aspect ratio and 2K resolution, generated through the Kie.ai API directly (the same API supplier that powers SciFig's production stack). Each prompt was 1,100–1,800 characters of detailed scientific specification — receptors, kinases, equations, named domains, color preferences. We graded each output on six dimensions: two objective (prompt fidelity, instruction adherence) and four subjective with explicit rubrics (scientific accuracy, publication readiness, readability, aesthetic quality). For every subjective score we recorded the reasoning, so the assessment is reproducible by an outside reader.

Both models were tested on the same day under the same parameters. The complete prompt set, the 24 generated images, and the full rubric-based scoring matrix are all published at /inspiration?model=gpt-image-2 and /inspiration?model=nano-banana-pro. If you re-run any prompt and get a different result, we want to know — that's how this kind of evaluation gets better over time.
This benchmark is not the final word, but it is the first systematic side-by-side that puts both flagship models through 10 scientific disciplines. The companion piece — GPT Image 2 vs Nano Banana Pro: Which AI Wins for Scientific Figures in 2026? — turns these findings into a "which one should I open today?" framework. Read it next if you want the verdict without the data table.

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